Buy Isentress 400mg (Raltegravir) comes as a tablet, a chewable tablet, and as an oral suspension to take by mouth. Raltegravir (Isentress®) tablets, chewable tablets, and oral suspension are usually taken with or without food twice a day. Raltegravir (Isentress® HD) tablets are usually taken with or without food once a day. Take raltegravir at the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.